According to additional findings from the Look AHEAD study, individuals with evidence of type 2 diabetes remission through diet and lifestyle changes experienced a 40% lower rate of cardiovascular disease and a 33% lower rate of chronic kidney disease compared to those without remission. Among children with overweight or obesity, the risk of developing type 2 diabetes was 72 times higher in those with baseline HbA1c levels of 6.3% to 6.4% compared to those with levels under 5.5%. The JDRF has awarded $9 million to fund a clinical trial testing the dual SGLT1 and SGLT2 inhibitor sotagliflozin for the treatment of kidney complications in patients with type 1 diabetes. A recent thyroid microwave ablation procedure was performed for the first time in the U.S. by a Utah interventional endocrinologist. Drinking cow’s milk may have a protective effect against type 2 diabetes in lactase non-persistent individuals, possibly due to the involvement of gut microbiota and blood metabolites. The reduction of social isolation and loneliness in people with obesity from the highest to the lowest level decreased their all-cause mortality risk from 36% to 9%. The list price for semaglutide (Ozempic) increased by 3.5% to around $970 for a month’s supply, while the price for tirzepatide (Mounjaro) rose by 4.5% to approximately $1,070. A study by Epic Research found that around 56% of patients either maintained the same weight or continued to lose weight a year after stopping semaglutide (Ozempic, Wegovy) or liraglutide (Saxenda). Ohio may soon join the ranks as the second state to restrict gender-affirming care in adults, while South Carolina lawmakers have approved a bill banning health professionals from providing such care to minors. An oral form of insulin was found to lower blood sugar levels without causing hypoglycemia in a baboon study. Stress during adolescence was associated with a higher cardiometabolic risk in young adulthood. The European Medicines Agency will review the expanded use of the weight-loss formulation of semaglutide to reduce the risk of strokes and heart attacks.




